admin
11-12-2018, 05:19 AM
The veterinary fenbendazole powder is a benzimidazole, which has a broad-spectrum deworming effect, is sensitive to nematodes, and has a strong effect on aphids and trematodes, and is ineffective against schistosomiasis. The mechanism of action mainly plays a role in the binding of the tubulin to the tubulin of the nematode. After oral administration, only a small amount was absorbed. Ruminants absorb slowly and monogastric animals are slightly faster. After the dog is taken orally, the blood concentration peak time is hour, and the sheep is 2-3 days. The absorbed fenbendazole is metabolized to sub-ape (active phenfenazole) and guanidine. In cattle, sheep and pigs, 44%-50% of fenbendazole is excreted from the original form, and less than 1% is excreted in the urine.
[Identification] Take the veterinary drug fenbendazole powder, add methanol to make a solution containing about 152g of fenbendazole per 1ml, filter it; take the filtrate, according to UV-visible spectrophotometry (Appendix 23), at 218nm There is maximum absorption at a wavelength of 294 nm.
[Check] Take the weight loss of this product and dry it to constant weight at 105 °C. The weight loss should not exceed 2.8% (Appendix 69).
Appearance uniformity Take the appropriate amount of the test sample, put it on a smooth paper, tiling about 5cm2, flatten its surface, and observe it under a bright background, it should have uniform color, no pattern and stain.
The quantity is checked according to the "Minimum Quantity Inspection Method" (gravimetric method), the average capacity is not less than 50g, and the amount of each bag should be 49g~52g.
[Content determination] Accurately weigh the appropriate amount of veterinary drug fenbendazole powder (about 30mg of fenbendazole), put it in a 100ml volumetric flask, add 90ml of methanol, dissolve fenbendazole by ultrasound, add alcohol to the scale, shake up Filtration, precise amount of continuous filtrate 5ml, placed in a 100ml volumetric flask, diluted to the mark with methanol, shake well, according to UV-visible spectrophotometry (Appendix 23),
The absorbance was measured at a wavelength of 294 nm, and the absorption coefficient of C15H13N3O2S was 490, which was obtained.
The main function of veterinary drug fenbendazole powder: for parasitic diseases such as nematode and tsutsugamushi disease in livestock and poultry.
1. Adult larvae, larvae, larvae, horse-tailed nematodes, A. elegans, A. elegans, Oryza sativa, and A. elegans.
2. Adults and larvae of the cattle Oster nematode, Haemonchus, Nematode, Nematode, Cooper nematode, Echinochloa, Esophageal nematodes, Nematodes, Fasciola, Moniz.
3. Various parasites in and out of sheep, goats and pigs.
4. It kills nematodes (adults and larvae), trematodes, worms and ectoparasites (blood cockroaches, beer, cockroaches). It can effectively control the weight loss, anemia, rough hair, malnutrition, dermatitis and paroxysmal cough caused by parasitic infection in pigs. Pigs that can be safely used at all stages of the farm. This product has a good killing effect on various parasites inside and outside the pig.
Veterinary drug fenbendazole powder product features:
1. Wide spectrum of insect resistance and thorough deworming; not only the killing rate of nematodes such as aphids, whipworms, hookworms, kidneyworms, and pulmonary filars is 100%, killing aphids, trematodes, blood stasis, cockroaches, cockroaches, etc. With a rate of more than 99%, it can almost completely kill parasites that harm pig farms; it can completely and completely eliminate pigs and ectoparasites; it not only has a killing effect on adult and extracorporeal parasitic arthropods, but also effectively kills development. Larvae of the period and transition period.
2, good palatability, large security range
Safe for young animals and pregnant sows, does not affect the immunity and production performance of animal organisms, can be used with confidence.
3, stable quality, high bioavailability
The special high-speed dispersion process adds drug stability factor, which greatly reduces the damage of gastric acid to the drug and maximizes the efficacy of the drug.
4, can effectively kill eggs, fundamentally solve the parasitic power problem.
Veterinary drug fenbendazole powder Note:
(1) Single dose is generally ineffective for dogs and cats and must be used for 3 days.
(2) Disabled for horses for consumption.
(3) This product should not be used in lactating dairy cows, nor in the pre-pregnancy 45 days.
(4) The use of fenbendazole in early pregnancy of sheep may be associated with teratogenicity and embryotoxicity.
[Identification] Take the veterinary drug fenbendazole powder, add methanol to make a solution containing about 152g of fenbendazole per 1ml, filter it; take the filtrate, according to UV-visible spectrophotometry (Appendix 23), at 218nm There is maximum absorption at a wavelength of 294 nm.
[Check] Take the weight loss of this product and dry it to constant weight at 105 °C. The weight loss should not exceed 2.8% (Appendix 69).
Appearance uniformity Take the appropriate amount of the test sample, put it on a smooth paper, tiling about 5cm2, flatten its surface, and observe it under a bright background, it should have uniform color, no pattern and stain.
The quantity is checked according to the "Minimum Quantity Inspection Method" (gravimetric method), the average capacity is not less than 50g, and the amount of each bag should be 49g~52g.
[Content determination] Accurately weigh the appropriate amount of veterinary drug fenbendazole powder (about 30mg of fenbendazole), put it in a 100ml volumetric flask, add 90ml of methanol, dissolve fenbendazole by ultrasound, add alcohol to the scale, shake up Filtration, precise amount of continuous filtrate 5ml, placed in a 100ml volumetric flask, diluted to the mark with methanol, shake well, according to UV-visible spectrophotometry (Appendix 23),
The absorbance was measured at a wavelength of 294 nm, and the absorption coefficient of C15H13N3O2S was 490, which was obtained.
The main function of veterinary drug fenbendazole powder: for parasitic diseases such as nematode and tsutsugamushi disease in livestock and poultry.
1. Adult larvae, larvae, larvae, horse-tailed nematodes, A. elegans, A. elegans, Oryza sativa, and A. elegans.
2. Adults and larvae of the cattle Oster nematode, Haemonchus, Nematode, Nematode, Cooper nematode, Echinochloa, Esophageal nematodes, Nematodes, Fasciola, Moniz.
3. Various parasites in and out of sheep, goats and pigs.
4. It kills nematodes (adults and larvae), trematodes, worms and ectoparasites (blood cockroaches, beer, cockroaches). It can effectively control the weight loss, anemia, rough hair, malnutrition, dermatitis and paroxysmal cough caused by parasitic infection in pigs. Pigs that can be safely used at all stages of the farm. This product has a good killing effect on various parasites inside and outside the pig.
Veterinary drug fenbendazole powder product features:
1. Wide spectrum of insect resistance and thorough deworming; not only the killing rate of nematodes such as aphids, whipworms, hookworms, kidneyworms, and pulmonary filars is 100%, killing aphids, trematodes, blood stasis, cockroaches, cockroaches, etc. With a rate of more than 99%, it can almost completely kill parasites that harm pig farms; it can completely and completely eliminate pigs and ectoparasites; it not only has a killing effect on adult and extracorporeal parasitic arthropods, but also effectively kills development. Larvae of the period and transition period.
2, good palatability, large security range
Safe for young animals and pregnant sows, does not affect the immunity and production performance of animal organisms, can be used with confidence.
3, stable quality, high bioavailability
The special high-speed dispersion process adds drug stability factor, which greatly reduces the damage of gastric acid to the drug and maximizes the efficacy of the drug.
4, can effectively kill eggs, fundamentally solve the parasitic power problem.
Veterinary drug fenbendazole powder Note:
(1) Single dose is generally ineffective for dogs and cats and must be used for 3 days.
(2) Disabled for horses for consumption.
(3) This product should not be used in lactating dairy cows, nor in the pre-pregnancy 45 days.
(4) The use of fenbendazole in early pregnancy of sheep may be associated with teratogenicity and embryotoxicity.